scaRabee: Optimization Toolkit for Pharmacokinetic-Pharmacodynamic Models

A port of the Scarabee toolkit originally written as a Matlab-based application. scaRabee provides a framework for simulation and optimization of pharmacokinetic-pharmacodynamic models at the individual and population level. It is built on top of the neldermead package, which provides the direct search algorithm proposed by Nelder and Mead for model optimization.

Version: 1.1-4
Depends: neldermead (≥ 1.0-8), optimsimplex (≥ 1.0-5), optimbase (≥ 1.0-8)
Imports: lattice, grid, deSolve, utils
Suggests: knitr (≥ 1.28), rmarkdown (≥ 2.2)
Published: 2022-02-04
DOI: 10.32614/CRAN.package.scaRabee
Author: Sebastien Bihorel [aut, cre]
Maintainer: Sebastien Bihorel <sb.pmlab at>
License: GPL-3
NeedsCompilation: no
Materials: README ChangeLog
In views: Pharmacokinetics
CRAN checks: scaRabee results


Reference manual: scaRabee.pdf
Vignettes: manual


Package source: scaRabee_1.1-4.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): scaRabee_1.1-4.tgz, r-oldrel (arm64): scaRabee_1.1-4.tgz, r-release (x86_64): scaRabee_1.1-4.tgz, r-oldrel (x86_64): scaRabee_1.1-4.tgz
Old sources: scaRabee archive


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