DNA copy number changes (gains and losses) are commonly seen in tumor tissue. Although these events occur randomly throughout the genome, some provide a selective growth advantage because they lead to increased (gains) or decreased (losses) expression of affected genes. MVisAGe was designed to help users explore the effects of copy number changes and alterations in DNA methylation status on gene expression. Gene-level Pearson and Spearman correlation coefficients are computed and plotted according to the genomic position of the underlying genes.


Please refer to the vignette.