seqCBS: Copy Number Profiling using Sequencing and CBS
This is a method for DNA Copy Number Profiling using
Next-Generation Sequencing. It has new model and test
statistics based on non-homogeneous Poisson Processes with
change point models. It uses an adaptation of Circular Binary
Segmentation. Also included are methods for point-wise Bayesian
Confidence Interval and model selection method for the
change-point model. A case and a control sample reads (normal
and tumor) are required.
||R (≥ 2.10), clue
||Jeremy J. Shen, Nancy R. Zhang
||Jeremy J. Shen <jeremyjshen at gmail.com>
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