msigdbr: MSigDB Gene Sets for Multiple Organisms in a Tidy Data Format

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The msigdbr R package provides Molecular Signatures Database (MSigDB) gene sets typically used with the Gene Set Enrichment Analysis (GSEA) software:


The package can be installed from CRAN.



The package data can be accessed using the msigdbr() function, which returns a data frame of gene sets and their member genes. For example, you can retrieve mouse genes from the C2 (curated) CGP (chemical and genetic perturbations) gene sets.

genesets = msigdbr(species = "Mus musculus", category = "C2", subcategory = "CGP")

Check the documentation website for more information.