This R package includes a suite of descriptive and inferential methods designed to evaluate one or more biomarkers for their ability to guide patient treatment recommendations. relevant functions are:
trtsel_measuresfor evaluating the performance of a user-specified marker-based treatment rule
trtselfor creating trtsel objects
plot.trtselfor plotting risk curves and more
evaluate.trtselfor evaluating marker performance
calibrate.trtselfor assessing model calibration
compare.trtselto compare two trtsel objects.
To dowload the package from CRAN, type:
To download and install the most recent version of the package directly from github, type:
if (!require("devtools")) install.packages("devtools") devtools::install_github("TreatmentSelection", "mdbrown")
A manuscript describing the methods employed in the package can be found here and a brief tutorial is available here.