OptimalGoldstandardDesigns: Design Parameter Optimization for Gold-Standard Non-Inferiority Trials

Methods to calculate optimal design parameters for one- and two-stage three-arm group-sequential gold-standard non-inferiority trial designs with or without binding or nonbinding futility boundaries, as described in Meis et al. (2023) <doi:10.1002/sim.9630>.

Version: 1.0.1
Depends: R (≥ 3.5)
Imports: nloptr, mvtnorm, cli, dplyr, tibble, Rdpack
Suggests: testthat (≥ 3.0.0), here, knitr, rmarkdown, covr, fpCompare, mnormt, future.apply
Published: 2023-09-11
DOI: NA
Author: Jan Meis ORCID iD [aut, cre]
Maintainer: Jan Meis <meis at imbi.uni-heidelberg.de>
License: GPL (≥ 3)
URL: https://github.com/jan-imbi/OptimalGoldstandardDesigns
NeedsCompilation: no
Citation: OptimalGoldstandardDesigns citation info
Materials: README
CRAN checks: OptimalGoldstandardDesigns results

Documentation:

Reference manual: OptimalGoldstandardDesigns.pdf
Vignettes: Introduction

Downloads:

Package source: OptimalGoldstandardDesigns_1.0.1.tar.gz
Windows binaries: r-devel: OptimalGoldstandardDesigns_1.0.1.zip, r-release: OptimalGoldstandardDesigns_1.0.1.zip, r-oldrel: OptimalGoldstandardDesigns_1.0.1.zip
macOS binaries: r-release (arm64): OptimalGoldstandardDesigns_1.0.1.tgz, r-oldrel (arm64): OptimalGoldstandardDesigns_1.0.1.tgz, r-release (x86_64): OptimalGoldstandardDesigns_1.0.1.tgz, r-oldrel (x86_64): OptimalGoldstandardDesigns_1.0.1.tgz
Old sources: OptimalGoldstandardDesigns archive

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